• In the News

Rethinking bedtime resistance in children with autism: is restless legs syndrome to blame?

SleepCharge's Chief Medical Officer Dr. Jeffrey Durmer was published this month in the Journal of Clinical Sleep Medicine on restless legs syndrome in children with autism.​

Authors: A Michelle L. Kanney, MD, Jeffrey S. Durmer, MD, PhD, Lynn Marie Trotti, MD, MSc, Roberta Leu, MD
Excerpt from the Journal of Clinical Sleep Medicine:

Study objectives: In this study we investigated the clinical correlates of restless legs syndrome in children with autism and report on our experiences with response to treatment.

Methods: A retrospective chart review of children seen in our sleep center from 2016-2019 was performed to identify children with autism and chronic insomnia. Patients underwent clinical assessments for restless legs symptomatology. Overnight polysomnogram, serum ferritin testing, and response to clinical treatment data were collected.

Results: A total of 103 children with autism and chronic insomnia were identified (age range 2-19 years). Of these, 41 children (39%) were diagnosed with restless legs syndrome. The diagnosis of restless legs syndrome was associated with significantly lower serum ferritin levels (mean 29 ± 18.62 ng/mL vs non-restless legs syndrome 56.7 ± 17.59, P < .001) and higher periodic limb movements of sleep on polysomnogram (8.12 ± 6.6 vs non-restless legs syndrome 0.06 ± 0.17). The presence of leg kicking, body rocking, or any symptoms involving the legs was highly correlated with the diagnosis of restless legs syndrome. Positive treatment response was noted in nearly all treated patients, including those treated with oral iron supplementation alone (25 children, 23 responders), gabapentin alone (12 children, all responders), and combination therapy (3 children, all responders).

Conclusions: Our findings suggest restless legs syndrome may represent an under-recognized cause of insomnia in children with autism. Initial assessment should include a thorough query of behaviors related to nocturnal motor complaints, because restless legs syndrome may be a treatable cause of sleep disruption.

Read More »

SleepCharge

A virtual health care provider focused on improving health and well-being through sleep.

Sleep care,

delivered virtually.

Everyone knows the importance of a good night's sleep—especially those who never get one.
Learn more

For further press inquiries, please get in touch.

Contact

SleepCharge
5000 Research Court
Suite 500
Suwanee, GA 30024
United States
Tel. 877-615-7257

Fax. 678-623-3990
Copyright © 2006-2020 Nox Health® and SleepCharge® are trademarks of Nox Health Group or affiliates.
Legal DisclaimerPrivacy Policy